Sildenafil for "blue babies". Such unlicensed drug use might be justified as last resort.
نویسندگان
چکیده
منابع مشابه
Women taking the “blue pill” (sildenafil citrate): such a big deal?
For years, phosphodiesterase type 5 inhibitors have been used for the treatment of erectile dysfunctions. Due to the similarities between male and female sexual response, several studies have assessed the effects of sildenafil citrate (Viagra(®)) in women affected by female sexual arousal disorder. The results are still conflicting and the drug is not devoid of adverse effects. Furthermore, fem...
متن کاملUnlicensed and off label drug use in neonates.
AIM To determine the extent of use of drugs that are either not licensed (unlicensed), or are outside the terms of their product licence (off label) in a neonatal intensive care unit. METHODS A prospective study was conducted over 13 weeks. RESULTS 455 prescription episodes were administered to 70 babies. 63 (90%) patients were given a drug that was either unlicensed or used in an off label...
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Background: Chronic drug abuse and sexual dysfunction specifically erectile dysfunction may lead drug abusers to seek over-the-counter or non-prescription medications, out of which Sildenafil citrate, sold as the trade name of Viagra® can be considered as a prime and important treatment. Therefore, the research purpose was to draw a comparison and review the role of methamphetamine abuse and si...
متن کاملSildenafil in Infants and Children
Pulmonary arterial hypertension (PAH) management has been transformed in recent times with the advent of cheap and effective diagnostic tools and therapy. Sildenafil, a phosphodiesterase-V inhibitor, has been at the centre of this treatment, and its success in treating PAH has led to its widespread uptake in adult and paediatric pulmonary hypertension (PH), as a first line treatment choice. Thi...
متن کاملThe utility of recombinant factor VIIa as a last resort in trauma
INTRODUCTION The use of recombinant factor VII (rFVIIa) as a last resort for the management of coagulopathy when there is severe metabolic acidosis during large bleedings in trauma might be deemed inappropriate. The objective of this study was to identify critical degrees of acidosis and associated factors at which rFVIIa might be considered of no utility. METHODS All massively transfused (≥ ...
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عنوان ژورنال:
- BMJ
دوره 325 7373 شماره
صفحات -
تاریخ انتشار 2002